Status:

COMPLETED

The Effects of High Spinal Anesthesia on Heart Function, Stress Response and Pain Control in Aortic Valve Surgery

Lead Sponsor:

University of Manitoba

Collaborating Sponsors:

St. Boniface Hospital

Health Sciences Centre Foundation, Manitoba

Conditions:

Aortic Stenosis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study is looking at the effects of high spinal anesthesia (also known as total spinal anesthesia) combined with general anesthesia versus general anesthesia alone on the following: Stress respon...

Detailed Description

It is hypothesized that high spinal anesthesia combined with general anesthesia decreases the intraoperative stress and inflammatory response and improve post-operative pain control and respiratory fu...

Eligibility Criteria

Inclusion

  • Undergoing surgery for aortic valve replacement due to aortic stenosis with or without CABG.

Exclusion

  • INR \> 1.4, PTT \> 40 seconds
  • platelet count \< 80, 000 per microlitre
  • local infection or deformity at the site of administration of the spinal anesthetic
  • raised intracranial pressure or evolving neurological deficit at the time of surgery

Key Trial Info

Start Date :

February 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2013

Estimated Enrollment :

14 Patients enrolled

Trial Details

Trial ID

NCT00348920

Start Date

February 1 2007

End Date

July 1 2013

Last Update

July 24 2013

Active Locations (1)

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1

St. Boniface General Hospital

Winnipeg, Manitoba, Canada, R2H 2A6