Status:
WITHDRAWN
Transcranial Magnetic Stimulation (TMS) Effects on Pain Perception
Lead Sponsor:
Medical University of South Carolina
Collaborating Sponsors:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Pain
Trigeminal Neuralgia
Eligibility:
All Genders
21-60 years
Phase:
PHASE2
PHASE3
Brief Summary
The purpose of this study is to investigate the effects of transcranial magnetic stimulation on pain perception.
Detailed Description
Chronic pain represents a huge public health concern and is generally poorly understood at a basic neurobiological level. Transcranial magnetic stimulation (TMS) is a non-invasive technique that uses ...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- For Healthy Adults:
- Between age of 21 and 60
- No prescription medications in previous 3 months
- No seizure history
- No depression
- Not suicidal
- No anxiety
- No hospitalizations or surgeries in previous 6 months
- No history of chronic pain conditions
- No implanted metal devices (e.g., pacemakers, metal plates, wires)
- Not pregnant
- No alcohol abuse/dependence history in previous 6 months
- No illicit drug use in previous 6 months
- Capable of reading, writing, giving consent, following instructions
- No history of brain surgery or history of loss of consciousness \>15 minutes
- No history of autoimmune or endocrine disorder
- No significant anxiety about entering MRI scanner
- For Patients with neuropathic pain:
- Between age of 21 and 75
- No seizure history
- Not taking medications shown to increase seizure risk (6 months)
- Not suicidal
- No hospitalizations or surgeries in previous 3 months
- No implanted metal devices (e.g., pacemakers, metal plates, wires)
- Not pregnant
- No alcohol abuse/dependence history in previous 6 months
- No illicit drug use in previous 6 months
- Capable of reading, writing, giving consent, following instructions
- Chronic pain (\>6 months), not significantly relieved by pharmacological treatment
- No significant anxiety about entering MRI scanner
Exclusion
Key Trial Info
Start Date :
July 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2010
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00349050
Start Date
July 1 2006
End Date
October 1 2010
Last Update
April 30 2012
Active Locations (1)
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1
Brain Stimulation Laboratory, Department of Psychiatry and Behavioral Sciences Medical University of South Carolina 5-North, IOP, 67 President Street
Charleston, South Carolina, United States, 29425