Status:

WITHDRAWN

The Effect of High Dose Vitamin C in Burn Patients

Lead Sponsor:

United States Army Institute of Surgical Research

Collaborating Sponsors:

University of Miami

Conditions:

Burns

Eligibility:

All Genders

18-72 years

Phase:

NA

Brief Summary

The purpose of this study is to see if intravenous Vitamin C will decrease the amount of IV fluids needed following burn injury in the first 48 hours.

Detailed Description

Adequate fluid resuscitation in burn injured patients to allow adequate renal blood flow has been the hallmark of burn care in the last 50 years. The danger of exceeding the optimal intravenous fluid ...

Eligibility Criteria

Inclusion

  • \>/= 20% total body surface area full and partial thickness burns
  • Admitted to the USAISR burn center within 10 hours post injury

Exclusion

  • Pregnant or breast feeding
  • Documented preadmission or admission renal failure
  • History of glucose-6-phosphate dehydrogenase deficiency, kidney stoves, gout or sickle cell
  • Electrical injury
  • Renal replacement of any kind\<24 hours after admission

Key Trial Info

Start Date :

July 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2008

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00350077

Start Date

July 1 2006

End Date

March 1 2008

Last Update

December 20 2011

Active Locations (1)

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1

United States Army Institute of Surgical Research

Fort Sam Houston, Texas, United States, 78234