Status:

COMPLETED

Cognitive Therapy for Negative Symptoms and Functioning

Lead Sponsor:

University of Pennsylvania

Collaborating Sponsors:

National Alliance for Research on Schizophrenia and Depression

Conditions:

Schizophrenia

Schizoaffective Disorder

Eligibility:

All Genders

18-65 years

Phase:

PHASE2

Brief Summary

This clinical trial tests the effectiveness of cognitive therapy (CT) to improve outcomes in outpatients diagnosed with schizophrenia or schizoaffective disorder who manifest prominent negative sympto...

Detailed Description

This is a clinical trial to evaluate the efficacy of adjunctive cognitive behavioral therapy for negative symptoms and functioning in chronic outpatients diagnosed with schizophrenia or schizoaffectiv...

Eligibility Criteria

Inclusion

  • Outpatient diagnosed with schizophrenia or schizoaffective disorder
  • Prominent negative symptoms (i.e., two global subscales rated "moderate" or higher on the Scale for the Assessment of Negative Symptoms
  • Proficiency in English
  • Able to give informed consent

Exclusion

  • Neurologic disease or damage
  • Systematic medical illnesses that may compromise neurocognitive functioning (e.g., insulin dependent diabetes, heart disease)
  • History of head injury or documented loss of consciousness
  • Physical handicaps that would interfere with assessment procedures

Key Trial Info

Start Date :

July 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2011

Estimated Enrollment :

61 Patients enrolled

Trial Details

Trial ID

NCT00350883

Start Date

July 1 2006

End Date

November 1 2011

Last Update

May 3 2012

Active Locations (1)

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1

Psychopathology Resarch Unit, Department of Psychiatry, University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104