Status:

COMPLETED

A Study to Assess the Effects of DPP-4 Inhibition on Insulin Sensitivity in Type 2 Diabetes

Lead Sponsor:

Novartis

Conditions:

Diabetes Mellitus, Type 2

Eligibility:

All Genders

21-65 years

Phase:

PHASE3

Brief Summary

Type 2 diabetes results when the body does not produce enough insulin and/or is unable to properly use the insulin it makes (insulin resistance). This study was undertaken to assess the effects of vil...

Eligibility Criteria

Inclusion

  • Diagnosed with type 2 diabetes at least 3 months prior to screening
  • Blood glucose criteria must be met
  • On stable dose of metformin therapy
  • BMI less than or equal to 39

Exclusion

  • Type 1 diabetes, diabetes resulting from pancreatic injury or secondary forms of diabetes
  • Treatment with thiazolidinediones or use of insulin within the previous 3 months
  • Significant illness within 2 weeks prior to dosing
  • High fasting triglycerides as defined by the protocol
  • Other protocol-defined inclusion/exclusion criteria may apply

Key Trial Info

Start Date :

February 1 2005

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2005

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT00351546

Start Date

February 1 2005

End Date

December 1 2005

Last Update

May 7 2012

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