Status:

COMPLETED

Comparison of Cephalexin Versus Clindamycin for Suspected CA-MRSA Skin Infections

Lead Sponsor:

Aaron Chen

Collaborating Sponsors:

Thrasher Research Fund

Johns Hopkins University

Conditions:

Staphylococcal Infection

Abscess

Eligibility:

All Genders

6-18 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to help define the role of antibiotics in the treatment of pediatric skin infections caused by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA). ...

Detailed Description

Community-associated methicillin resistant Staphylococcus Aureus (CA-MRSA) infections have increased significantly over the past decade. Nearly every major region of the country has reported infection...

Eligibility Criteria

Inclusion

  • Children between the ages of 6 months and 18 years of age (inclusive)
  • Suspected purulent staphylococcal skin or soft tissue infection
  • No hospitalization within the previous 14 days
  • Must have reliable means of follow-up contact (e.g. working phone)
  • Outpatient management in the judgement of treating physician

Exclusion

  • Hospitalization on initial visit
  • Voluntary withdrawal by the treating physician in order to dictate the antibiotic being used
  • Patients with a history of hypersensitivity to or intolerance of cephalexin (or other beta lactams) or clindamycin.
  • Patients with altered immunity (inherited or acquired)
  • Patients with skin infections related to surgical wounds or hardware.
  • Patients currently on antibiotic therapy

Key Trial Info

Start Date :

September 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2009

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT00352612

Start Date

September 1 2006

End Date

August 1 2009

Last Update

May 13 2013

Active Locations (1)

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Johns Hopkins University

Baltimore, Maryland, United States, 21287