Status:
COMPLETED
Determining the Response to Sipping Beverages Without Swallowing in People With Eating Disorders
Lead Sponsor:
New York State Psychiatric Institute
Collaborating Sponsors:
National Institute of Mental Health (NIMH)
Conditions:
Eating Disorders
Eligibility:
FEMALE
16-45 years
Brief Summary
This study will use a sipping and spitting exercise to better understand the brain's response to food intake in people with eating disorders.
Detailed Description
Eating behavior is controlled by many factors, including appetite; food availability; family, peer, and cultural practices; and attempts at voluntary control. Eating disorders are characterized by a v...
Eligibility Criteria
Inclusion
- For participants with bulimia nervosa:
- Meets DSM-IV criteria for bulimia nervosa
- Duration of illness is 1 year
- Self-induces vomiting
- Weighs between 85 and 120% of ideal weight
- For participants with anorexia nervosa:
- Meets DSM-IV criteria for anorexia nervosa (amenorrhea will not be required for study inclusion)
- Medically stable
- For participants with binge eating disorder:
- Meets DSM-IV criteria for binge eating disorder
- Duration of illness is 1 year
- Body Mass Index (BMI) is at least 30
- For healthy participants:
- Weighs between 80 and 120% of ideal weight
Exclusion
- For participants with anorexia nervosa, bulimia nervosa, or binge eating disorder:
- Significant medical illness
- At risk for suicide
- Currently taking medication
- History of drug or alcohol abuse within 6 months prior to study entry
- Pregnant or breastfeeding
- Axis I psychiatric disorder requiring pharmacotherapy
- Axis I psychiatric disorder that could impair ability to participate in the study (e.g., mania, psychosis)
- Comorbid binge eating disorder and an Axis I illness other than major depression
- For healthy participants:
- Current or history of psychiatric illness
- History of any eating disorder
- Significant medical illness
- Currently taking medication
- History of drug or alcohol abuse within 6 months prior to study entry
- Pregnant or breastfeeding
Key Trial Info
Start Date :
April 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2011
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT00353548
Start Date
April 1 2005
End Date
July 1 2011
Last Update
July 23 2012
Active Locations (1)
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1
New York State Psychiatric Institute/Columbia University Medical Center
New York, New York, United States, 10032