Status:

COMPLETED

Bioavailability of Insulin Administered in Duodenum

Lead Sponsor:

University of Aarhus

Collaborating Sponsors:

Aarhus University Hospital

Conditions:

Diabetes Mellitus

Eligibility:

All Genders

18-50 years

Phase:

PHASE1

PHASE2

Brief Summary

A study of the bioavailability of insulin after infusion in the duodenum in healthy volunteers.

Detailed Description

METHODOLOGY All subjects will be admitted fasting to the Clinical Trial Unit at Århus Community Hospital at 8 a.m. A Gastrointestinal tube will be placed in Duodenum distal to papilla Vaterii with a p...

Eligibility Criteria

Inclusion

  • Signed informed consent
  • Healthy Volunteers
  • Age \>18 - \< 50 years
  • BMI 18-30 kg/m2

Exclusion

  • Any history of gastrointestinal or endocrine disorders (e.g. diabetes mellitus)
  • pregnancy or nursing
  • suspected or known allergy towards the drug
  • Participation in other research trials within 3 months before the study

Key Trial Info

Start Date :

August 1 2006

Trial Type :

INTERVENTIONAL

End Date :

December 1 2006

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT00353990

Start Date

August 1 2006

End Date

December 1 2006

Last Update

April 25 2007

Active Locations (1)

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1

Medical Department M

Aarhus, Aarhus, Denmark, DK-8000 C