Status:

COMPLETED

Using Minimally Invasive Cardiac Output Data vs. Standard Care for Patients Emergently Admitted to the Intensive Care Unit Who Are Hemodynamically Unstable

Lead Sponsor:

Edwards Lifesciences

Conditions:

Cardiac Output, High

Cardiac Output, Low

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to evaluate if the continuous availability of minimally invasive cardiac output data during treatment in the intensive care unit (ICU) for hemodynamic instability, in comp...

Detailed Description

Hemodynamic instability during the first 24-hours of Intensive Care Unit (ICU) admission is associated with increased risk of subsequent morbidity and mortality. Goal-directed hemodynamic support has ...

Eligibility Criteria

Inclusion

  • Patient newly admitted to the ICU due to an emergency unplanned admission.
  • Patient diagnosed with hemodynamic instability at or becomes unstable within 6 hours of ICU admission.
  • Patient must require an indwelling radial or a femoral artery catheter.
  • Patient is included in the study according to the specific regulations of the participating center: this may include a deferred consent, consent by designee, consent by independent physician or a combination thereof.
  • Patient must be 18 years old or older.

Exclusion

  • Patients with contraindications for the placement of radial, femoral, dorsalis pedis, or other arterial cannula.
  • Patients with a pulmonary artery catheter.
  • Patients who are hemodynamically stable.
  • Patients with history or clinical findings of aortic valve regurgitation.
  • Patients being treated with an intra-aortic balloon pump.
  • Female patient is pregnant.
  • Patient is currently participating in an investigational drug or another device study.

Key Trial Info

Start Date :

July 1 2006

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2007

Estimated Enrollment :

392 Patients enrolled

Trial Details

Trial ID

NCT00354211

Start Date

July 1 2006

End Date

December 1 2007

Last Update

February 11 2013

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Kuopio University Hospital

Kuopio, Finland, 70211

2

Tampere Unversity Hospital

Tampere, Finland, 33521

3

University Hospital Bern (Inselspital)

Bern, Switzerland, 3010