Status:

TERMINATED

Comparison Between Radiofrequency Versus Ethanol Injection for the Treatment of Hepatocellular Carcinoma

Lead Sponsor:

Azienda Ospedaliera San Giovanni Battista

Conditions:

Carcinoma, Hepatocellular

Eligibility:

All Genders

Phase:

PHASE3

Brief Summary

Ethanol injection has been for many years the standard approach as percutaneous treatment of non-surgical early hepatocellular carcinoma in cirrhotic patients. Radiofrequency ablation has been propose...

Detailed Description

Currently early hepatocellular carcinoma (HCC) complicating liver cirrhosis is often treated by percutaneous ablation techniques under ultrasound guidance: their performance is easy, safe and efficien...

Eligibility Criteria

Inclusion

  • Included were cirrhotic patients in Child-Pugh class A/B with 1 to 3 HCC nodes of ≤ 30mm in diameter.

Exclusion

  • Excluded were patients without liver cirrhosis, in Child-Pugh class C, with a platelets count \<40000, INR \>1.75, PTT \>40sec, hypo vascular HCC, lesions not detectable by ultrasonography (US), lesions close (≤1cm) to the gallbladder, hepatic hilum, colon or stomach, with venous invasion or metastatic disease

Key Trial Info

Start Date :

January 1 2001

Trial Type :

INTERVENTIONAL

End Date :

March 1 2006

Estimated Enrollment :

240 Patients enrolled

Trial Details

Trial ID

NCT00355212

Start Date

January 1 2001

End Date

March 1 2006

Last Update

July 25 2006

Active Locations (1)

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Azienda Ospedaliera San Giovanni Battista di Torino

Torino, Italy, 10126