Status:

COMPLETED

Effectiveness of Pacemaker With Closed Loop Stimulation Compared to Pacemakers With and Without Standard Rate Response

Lead Sponsor:

Biotronik, Inc.

Conditions:

Bradycardia

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

This is a randomized, prospective, single-blinded, multi-center study involving approximately 1500 patients at 100 centers. The purpose of this study is to demonstrate the effectiveness of Closed Loop...

Detailed Description

All patients enrolled in the CLEAR study are implanted with a Cylos pacemaker with Closed Loop Stimulation (CLS) rate adaption technology. Any legally marketed pacing leads may be implanted with the C...

Eligibility Criteria

Inclusion

  • Implanted within the last 45 days or being considered for implant with a BIOTRONIK pacemaker utilizing CLS rate adaptation technology (currently the Cylos family of pacemakers).
  • Ability to give written informed consent
  • Geographically stable and able to return for regular follow-ups for 12 months after ADL testing
  • At least 18 years old

Exclusion

  • Patients physically limited and unable to perform all or parts of the ADL testing
  • Currently enrolled in any other clinical study
  • Patients with medical reasons that preclude regular participation in the follow-ups

Key Trial Info

Start Date :

May 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2010

Estimated Enrollment :

1491 Patients enrolled

Trial Details

Trial ID

NCT00355797

Start Date

May 1 2006

End Date

December 1 2010

Last Update

December 20 2012

Active Locations (99)

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Page 1 of 25 (99 locations)

1

Raymond Fernandez

Albertville, Alabama, United States, 35951

2

Cardiology Associates-Gadsden

Gadsden, Alabama, United States, 35901

3

North Alabama Cardiology Center

Gadsden, Alabama, United States, 35901

4

Richard Kim, MD

Jasper, Alabama, United States, 35501