Status:

COMPLETED

Vascular and Skeletal Protective Effects of Genistein in Postmenopausal Women

Lead Sponsor:

University of Messina

Conditions:

Menopause

Osteopenia

Eligibility:

FEMALE

45-70 years

Phase:

PHASE2

PHASE3

Brief Summary

The present research program is proposed deepening some pharmacological effects of the genistein therapy in order to individualize alternative treatments to the conventional hormonal replacement thera...

Detailed Description

Genistein is a phytoestrogen of the isoflavone family which has been shown to have beneficial effects on endothelial function and bone metabolism. On the basis of the so far obtained results, aim of o...

Eligibility Criteria

Inclusion

  • At least one year of menopause
  • No use of hormone replacement therapy
  • Bone mineral density T-score at the femoral neck minor than one S.D.

Exclusion

  • Concomitant disease
  • Smoke habit

Key Trial Info

Start Date :

January 1 2003

Trial Type :

INTERVENTIONAL

End Date :

June 1 2005

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT00355953

Start Date

January 1 2003

End Date

June 1 2005

Last Update

April 22 2008

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Vascular and Skeletal Protective Effects of Genistein in Postmenopausal Women | DecenTrialz