Status:

COMPLETED

D-cycloserine and Virtual Reality Exposure to Treat Iraq War Veterans With PTSD

Lead Sponsor:

Emory University

Collaborating Sponsors:

National Institute of Mental Health (NIMH)

Conditions:

Stress Disorder, Post Traumatic

Eligibility:

All Genders

21-65 years

Phase:

PHASE2

PHASE3

Brief Summary

This study will determine whether a combination of virtual reality exposure therapy and D-cycloserine will reduce post-traumatic stress disorder symptoms in Iraq war veterans.

Detailed Description

Post-traumatic stress disorder (PTSD) is a type of anxiety disorder affecting people who have witnessed or experienced a traumatic event. Veterans of war are at an increased risk for developing PTSD b...

Eligibility Criteria

Inclusion

  • Meets DSM-IV criteria for PTSD due to Iraq military trauma
  • Speaks English
  • Healthy overall

Exclusion

  • History of mania, schizophrenia, or other psychoses
  • Suicidal
  • Current alcohol or drug dependence
  • Medication free within 2 weeks of study entry for any medication that has been taken less than daily for the past month and medicine free within 4 weeks of study entry for any anxiolytic medication that has been taken daily for the last month or more
  • Pregnant
  • Special medical conditions, such as kidney insufficiency, chronic diseases, or history of significant head injury
  • Stabilized on potentially data obscuring medication such as glucocorticoids

Key Trial Info

Start Date :

September 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2014

Estimated Enrollment :

156 Patients enrolled

Trial Details

Trial ID

NCT00356278

Start Date

September 1 2006

End Date

June 1 2014

Last Update

January 8 2016

Active Locations (1)

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1

Emory University

Atlanta, Georgia, United States, 30329