Status:

COMPLETED

Study Of Sumatriptan Succinate Injection Kit In Patients With Migraine or Cluster Headache In Japan

Lead Sponsor:

GlaxoSmithKline

Conditions:

Migraine Disorders

Eligibility:

All Genders

18-65 years

Phase:

PHASE3

Brief Summary

This study will be conducted to collect cases treated by self-injection of sumatriptan 3mg kit product for the treatment of migraine or cluster headache attacks in clinical settings, to demonstrate th...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Diagnosis of migraine (with or without aura) or cluster headache according to the International Classification of Headache Disorders, Version 2 (ICHD-II)
  • History of migraine or cluster headache persisting for at least 6 months
  • Migraine: One to 6 attacks of moderate or severer headaches per month during the 2 months prior to enrollment
  • Cluster Headache: Each attack persisting for at least 45 minutes
  • Written informed consent obtained from the patient. When a patient is a minor, written informed consent from his/her proxy consenter (e.g., person with parental authority) will also be required.
  • Exclusion criteria:
  • History of hypersensitivity to any of the ingredients of 5-HT1B/1D receptor antagonists (e.g., triptans) or serious AE due to treatment with these drugs
  • History of serious adverse event attributable to treatment with Imigran® Injection 3
  • History of myocardial infarction, current or previous history of ischemic heart disease or its symptoms/signs, or current history of atypical variant angina (coronary arteriospasm)
  • Previous history of cerebrovascular disorder or transient cerebral ischemic attack
  • Current or previous history of peripheral angiopathy (including Raynaud's syndrome)
  • Systolic blood pressure (SBP) \>160 mmHg or diastolic blood pressure (DBP) \>95 mmHg at the start of treatment period
  • Current familial hemiplegic migraine, basilar migraine, or sporadic hemiplegic migraine
  • Current abuse of ergotamine- or dihydroergotamine-containing preparations or triptans
  • Pregnant women, lactating mothers, women who may be pregnant, or women of childbearing potential using no appropriate contraceptive measures.
  • Epilepsy or organic cerebral disorder which may lead to convulsion
  • Previous history of hypersensitivity to sulfonamides
  • Known drug allergy or idiosyncrasies
  • Known drug dependency or alcoholism

Exclusion

    Key Trial Info

    Start Date :

    June 20 2006

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    August 7 2006

    Estimated Enrollment :

    75 Patients enrolled

    Trial Details

    Trial ID

    NCT00356603

    Start Date

    June 20 2006

    End Date

    August 7 2006

    Last Update

    September 4 2018

    Active Locations (4)

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    Page 1 of 1 (4 locations)

    1

    GSK Investigational Site

    Aichi, Japan, 450-0002

    2

    GSK Investigational Site

    Hyōgo, Japan, 663-8204

    3

    GSK Investigational Site

    Kyoto, Japan, 600-8811

    4

    GSK Investigational Site

    Tokyo, Japan, 105-7103