Status:
COMPLETED
Relationship Between HIV and Malaria in Ugandan Children
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
HIV Infections
Malaria
Eligibility:
All Genders
1-10 years
Brief Summary
HIV and malaria are two of the most important diseases to afflict children in sub-Saharan Africa. However, it is unknown what relationships exist between the two diseases. The purpose of this study is...
Detailed Description
HIV and malaria are two of the most important infectious diseases in sub-Saharan Africa. By 2000, over 25 million children and adults were living with HIV/AIDS, and 16 million people had died of the d...
Eligibility Criteria
Inclusion
- HIV infected
- Resides within a 20 km (12.4 mi) radius of the study clinic in Kampala, Uganda
- Had a minimum of 1 regularly scheduled clinic visit in the 3 months prior to study entry
- Willing to return to the study clinic if fever or other illness occurs during this study
- Willing to avoid medications administered outside the Mulago Hospital Complex
- Parent or guardian willing to provide informed consent
Exclusion
- Intends to move more than 20 km (12.4 mi) from the study clinic during the follow-up period
- Weigh less than 5 kg (11 lbs)
- Participating in another Infectious Disease Clinic (IDC) cohort study
- Any current medical problem requiring in-patient evaluation or home care
- History of allergy or sensitivity to amodiaquine, artesunate, or quinine
- Life-threatening screening laboratory values in the absence of malaria. More information on this criterion can be found in the protocol.
Key Trial Info
Start Date :
November 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 1 2010
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT00356824
Start Date
November 1 2005
End Date
May 1 2010
Last Update
November 1 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Pediatric Infectious Diseases Clinic, Mulago Hospital Complex
Kampala, Uganda