Status:
COMPLETED
Ocular Pharmacokinetics After a Single Drop Instillation of T1225 0.5, 1, 1.5% in 91 Healthy Volunteers
Lead Sponsor:
Laboratoires Thea
Conditions:
Eye Infections, Bacterial
Eligibility:
All Genders
18-45 years
Phase:
PHASE1
Brief Summary
To evaluate azithromycin tear concentrations after instillation of one drop of one of the three T1225 concentrations (0.5%, 1% and 1.5%) and to evaluate the ocular safety.
Detailed Description
The aim of the present study was to compare azithromycin tear ocular concentrations after a single instillation of three different T1225 concentrations in order to determine early azithromycin tear co...
Eligibility Criteria
Inclusion
- Male/female aged from 18 to 45 years;
- Written informed consent;
- Healthy volunteers without any subjective ocular symptom;
- Corrected visual acuity \>= 6/10;
- Registered in the national register of healthy volunteers
Exclusion
- Ocular trauma, infection or inflammation within the last 3 months;
- Conjunctival hyperaemia (score \>= 2);
- Folliculo-papillary conjunctivitis (score \>= 2);
- Topical ocular treatment within the last month;
- Ocular surgery, including LASIK and PRK, within the last 12 months;
- Other ocular laser within the last 3 months;
- Zithromax® and Azadose® within the last 3 months;
- Medication during the study (except: paracetamol, contraceptives
Key Trial Info
Start Date :
May 1 2002
Trial Type :
INTERVENTIONAL
End Date :
June 1 2002
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00356850
Start Date
May 1 2002
End Date
June 1 2002
Last Update
July 26 2006
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.