Status:
COMPLETED
The Effects of Potassium Citrate on Bone Metabolism
Lead Sponsor:
Weill Medical College of Cornell University
Conditions:
Bone Diseases, Metabolic
Osteoporosis, Postmenopausal
Eligibility:
FEMALE
45-75 years
Phase:
PHASE4
Brief Summary
Skeletal buffering of chronic acid loads may contribute to a significant amount of bone loss over time. Evidence from a few small short-term studies suggests that basic compounds, namely potassium cit...
Detailed Description
Participants were recruited from a single academic center. Subjects underwent screening at the Clinical Translational Science Center (CTSC) at Weill Cornell Medical College (WCMC). Study visits occurr...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Postmenopausal women, more than 2 years post menopause
- Osteopenia, defined as a T score at the lumbar spine or total hip between -1.0 and -2.5
- No history of prior fragility fracture
- Exclusion criteria:
- Renal insufficiency
- Use of potassium sparing diuretics
- Use of potassium supplements
- Hyperkalemia
- Secondary causes of osteoporosis or metabolic bone disease
- Delayed gastric emptying
- esophageal compression, intestinal obstruction or stricture
- use of anticholinergic medication
- active urinary tract infection.
Exclusion
Key Trial Info
Start Date :
August 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2011
Estimated Enrollment :
83 Patients enrolled
Trial Details
Trial ID
NCT00357331
Start Date
August 1 2006
End Date
April 1 2011
Last Update
June 12 2017
Active Locations (1)
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1
Weill Cornell Medical College
New York, New York, United States, 10021