Status:
COMPLETED
Studies in Families With Corneal Dystrophy or Other Inherited Corneal Diseases
Lead Sponsor:
National Eye Institute (NEI)
Conditions:
Corneal Dystrophies, Hereditary
Corneal Disease
Eligibility:
All Genders
4+ years
Brief Summary
This study will explore the clinical and hereditary (genetic) features of corneal dystrophy and other inherited corneal disease. Corneal dystrophy is clouding of the cornea - the transparent part of t...
Detailed Description
Objective: This project, Clinical and Molecular Studies in Families With Corneal Dystrophy or Other Inherited Corneal Diseases will study the inheritance of corneal dystrophy and other inherited corne...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Subjects with the following will be recruited:
- Individuals or family members of individuals with corneal dystrophies and related corneal diseases.
- Adults must be capable of providing their own consent.
- All subjects must be able to cooperate with study examination and phlebotomy.
- Older than 4 years of age.
- EXCLUSION CRITERIA:
- Diseases, infections, or trauma that mimic corneal diseases.
- Children requiring sedation for study procedures.
Exclusion
Key Trial Info
Start Date :
October 6 2003
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 21 2016
Estimated Enrollment :
86 Patients enrolled
Trial Details
Trial ID
NCT00357435
Start Date
October 6 2003
End Date
July 21 2016
Last Update
December 12 2019
Active Locations (6)
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1
Jules Stein Eye Institute, UCLA
Los Angeles, California, United States
2
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892
3
Cleveland Clinic
Cleveland, Ohio, United States
4
University of Texas, Houston
Houston, Texas, United States, 77030