Status:
COMPLETED
Can Aprotinin Reduce Pancreatitis After Scoliosis Surgery
Lead Sponsor:
Nemours Children's Clinic
Conditions:
Pancreatitis
Eligibility:
All Genders
Up to 18 years
Phase:
PHASE1
Brief Summary
Pancreatitis is caused by an acute injury on the pancreas. This illness is associated with abdominal pain, vomiting or even fever. We have recently reported a high rate of acute pancreatitis developin...
Detailed Description
We have shown an association between high intraoperative blood loss in children and young adults undergoing posterior spinal fusion and a subsequent clinical course characterized by a high rate of acu...
Eligibility Criteria
Inclusion
- Children of all ages (\<18 yr or 18 yr), both boys and girls who undergo posterior spinal fusion with cebebral palsy or neuromuscular scoliosis.
Exclusion
- received Aprotinin previously
- have severe allergic reaction to medicine
- received whole blood transfusions
- bleeding disorder
- impaired renal function, liver or kidney impairment
- previous pancreatitis
- girls who are pregnant.
Key Trial Info
Start Date :
March 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00357851
Start Date
March 1 2005
Last Update
October 14 2010
Active Locations (1)
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1
Alfred I. duPont Hospital for Children
Wilmington, Delaware, United States, 19803