Status:
COMPLETED
Carbachol´s Headache Inducing Characteristics and Effects on the Cerebral Blood Flow
Lead Sponsor:
Danish Headache Center
Conditions:
Headache
Eligibility:
All Genders
18-40 years
Brief Summary
To investigate headache score and accompanying symptoms during and after infusion of carbachol.
Detailed Description
To investigate headache score and accompanying symptoms during and after infusion of carbachol. Changes in regional cerebral blood flow (rCBF) in the area supplied by middle cerebral artery (MCA), bl...
Eligibility Criteria
Inclusion
- Healthy volunteers
- Aged 18-40
- 50-100 kg
- Fertile women must use safe contraceptives (IUD, oral contraceptives, surgical sterilisation and long lasting gestagen.
Exclusion
- Tension type headache more than once/month
- Other primary headaches
- Daily medication except contraceptives
- Drug taken within 4 times the halflife for the specific drug except contraceptives
- Pregnant or lactating women
- Exposure to radiation within the last year
- Headache within the last 24 hours before start of trial
- Hypertension
- Hypotension
- Respiratory or cardiac disease
Key Trial Info
Start Date :
July 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2007
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT00357864
Start Date
July 1 2006
End Date
April 1 2007
Last Update
August 30 2007
Active Locations (1)
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1
Dansih Headache Center
Glostrup Municipality, Denmark, 2600