Status:
COMPLETED
The Role of Endothelium Dysfunction in Progression of CKD (Chronic Kidney Disease) After AKI (Acute Kidney Injury)
Lead Sponsor:
University of Alabama at Birmingham
Conditions:
Acute Renal Failure
Chronic Kidney Failure
Eligibility:
All Genders
2-20 years
Brief Summary
To understand how AKI (Acute Kidney Injury) leads to chronic kidney disease so therapies can be found to alter the progression of events thereby significantly impacting the long-term outcomes of child...
Detailed Description
This research study is designed to study what happens to the kidneys after they have an injury. There is some evidence that even if there appears to be great improvement of kidney function, an injury ...
Eligibility Criteria
Inclusion
- Children between age 2-20
- Decrease in renal function by 25% or greater
- Renal function has returned to normal
Exclusion
- History of chronic disease
- Cancer
- Congenital heart disease
- Organ Transplantation
- Liver disease
- Pulmonary disease
- Diabetes other primary metabolic condition
- Severe neurologic impairments
- Hypertension
- Auto-immune
- Infectious disease or renal disease
- Smokers
- Renal disease w/primary cause i.e. - HUS or Glomerulonephritis
- severe allergies including allergy to seafood and/or iodine
Key Trial Info
Start Date :
April 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2009
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT00358306
Start Date
April 1 2008
End Date
July 1 2009
Last Update
May 14 2020
Active Locations (1)
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1
University Of Alabama
Birmingham, Alabama, United States, 35233