Status:

COMPLETED

REMStar Auto With C-Flex - In-Laboratory Performance v. Conventionally Titrated CPAP Therapy: Performances and Preferences

Lead Sponsor:

University of British Columbia

Conditions:

Obstructive Sleep Apnoea Hypopnoea Syndrome

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study will evaluate the use of REMStar Auto with C-Flex (RSA C-Flex) therapy in subjects with previously diagnosed obstructive sleep apnea / hypopnea syndrome, during in-laboratory studies. The s...

Detailed Description

The research question we are exploring is whether the To determine if treatment with C-FLEX is at least equivalent to conventional CPAP therapy as evidenced by standard sleep and breathing variables a...

Eligibility Criteria

Inclusion

  • Age ≥ 18
  • Primary medical diagnosis Obstructive Sleep Apnea / Hypopnea Syndrome
  • AHI ≥ 15 events•hr-1 of sleep
  • Ability to provide consent
  • Successful completion of a conventional CPAP titration in a sleep laboratory under polysomnographic conditions (success defined by reduction of AHI to \< 5•hr-1 during therapeutic portion of study, in supine position and in REM and NREM sleep state).

Exclusion

  • Patients who are medically complicated or who are medically unstable.
  • Patients who have been on chronic CPAP or BiPAP therapy or require oxygen therapy.
  • Patients with respiratory failure or respiratory insufficiency or who have elevated arterial carbon dioxide levels while awake.
  • Patients who have had surgery of the upper airway, nose, sinus, or middle ear within the previous 90 days.
  • Patients with non-OSA sleep disorders.
  • Patients in whom PAP therapy is otherwise medically contraindicated.

Key Trial Info

Start Date :

February 1 2005

Trial Type :

INTERVENTIONAL

End Date :

December 1 2005

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT00358800

Start Date

February 1 2005

End Date

December 1 2005

Last Update

August 1 2006

Active Locations (1)

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1

UBC Sleep Disorder Program and Sleep Lab, UBC Hospital

Vancouver, British Columbia, Canada