Status:

TERMINATED

A Randomized Trial of Two Surgical Techniques for Pancreaticojejunostomy in Patients Undergoing Pancreaticoduodenectomy

Lead Sponsor:

Thomas Jefferson University

Conditions:

Pancreatic Neoplasms

Biliary Tract Neoplasms

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this trial is to determine whether a mucosa-to-mucosa technique of pancreaticojejunostomy will improve the pancreatic fistula rate.

Detailed Description

Pancreaticoduodenectomy (PD) is a commonly performed operative procedure which is used in selected patients with benign and malignant diseases of the pancreas and periampullary region. The procedure i...

Eligibility Criteria

Inclusion

  • Patients must have undergone pancreaticoduodenectomy.
  • Must have pancreatic remnant remaining in place (body and tail).
  • Must be candidate for reconstruction by pancreaticojejunostomy by one of the two techniques described below.
  • Must have an identifiable pancreatic duct which can be used for a duct-to-mucosa anastomosis.

Exclusion

  • Patients undergoing total pancreatectomy.
  • Patients undergoing PD who have had previous left-sided pancreatic resection.
  • Failure to sign informed consent.
  • Failure to identify the pancreatic duct.
  • Pregnant patients.

Key Trial Info

Start Date :

May 25 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 12 2008

Estimated Enrollment :

54 Patients enrolled

Trial Details

Trial ID

NCT00359320

Start Date

May 25 2006

End Date

July 12 2008

Last Update

May 2 2025

Active Locations (1)

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Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, United States, 19107