Status:

COMPLETED

Influence of Angiotensin Converting Enzyme (ACE) Genotype on Lung Diffusion in Heart Failure

Lead Sponsor:

Piergiuseppe Agostoni

Conditions:

Heart Failure, Congestive

Eligibility:

All Genders

20-80 years

Phase:

NA

Brief Summary

In patients with chronic heart failure ACE-inhibitor treatment improves lung diffusion and prevents pulmonary edema after fluid overload. In the western country, 3 population types of ACE genotypes ex...

Detailed Description

Patients with chronic heart failure in stable clinical condition treated with ACE-inhibitors, but not aspirin, will be evaluated by means of maximal cardiopulmonary exercise test and lung function inc...

Eligibility Criteria

Inclusion

  • New York Heart Association (NYHA) class I and II heart failure
  • Chronic ACE-inhibitor treatment

Exclusion

  • Aspirin treatment in the previous 2 months

Key Trial Info

Start Date :

August 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2013

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT00361127

Start Date

August 1 2006

End Date

December 1 2013

Last Update

January 28 2016

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Centro Cardiologico Monzino

Milan, Italy, 20138

Influence of Angiotensin Converting Enzyme (ACE) Genotype on Lung Diffusion in Heart Failure | DecenTrialz