Status:
TERMINATED
Comparative Study of the Protein C Pathway in Septic and Non Septic Patients With Organ Failure
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
Institut National de la Santé Et de la Recherche Médicale, France
Conditions:
Severe Sepsis
Organ Failure
Eligibility:
All Genders
18+ years
Brief Summary
This is a comparative study performed in 3 groups of patients/subjects: 30 severe sepsis patients, 30 non-septic patients with organ failure, 30 healthy subjects. The only intervention is a venous bl...
Detailed Description
analysis of the PC pathway * PC activity * PS activity * soluble thrombomodulin * soluble EPCR * activated protein C * quantitative flow cytometry on monocytes (thrombomodulin and EPCR) * whole blood...
Eligibility Criteria
Inclusion
- severe sepsis patients or:
- non-septic acute organ failure patients or:
- healthy subjects matched for age and sex with severe sepsis patients
Exclusion
- criteria for organ failure lasting for more than 24 hours
Key Trial Info
Start Date :
March 1 2003
Trial Type :
OBSERVATIONAL
End Date :
October 1 2003
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT00361725
Start Date
March 1 2003
End Date
October 1 2003
Last Update
August 15 2006
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