Status:
COMPLETED
Lung Rehabilitation in Treating Patients With Chronic Obstructive Pulmonary Disease Who Are Undergoing Surgery for Lung Cancer
Lead Sponsor:
Mayo Clinic
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Lung Cancer
Perioperative/Postoperative Complications
Eligibility:
All Genders
40-120 years
Phase:
NA
Brief Summary
RATIONALE: Exercise may help improve lung function and lessen complications of surgery in patients with chronic obstructive pulmonary disease who are undergoing surgery for lung cancer. It is not yet ...
Detailed Description
OBJECTIVES: Primary * Compare the impact of preoperative pulmonary rehabilitation (including upper and lower extremity resistance training) vs usual care in patients with lung cancer and moderate to...
Eligibility Criteria
Inclusion
- DISEASE CHARACTERISTICS:
- Diagnosis of lung cancer
- Scheduled to undergo any thoracotomy for lung cancer resection (including wedge) or VATS lobectomy or pneumonectomy for lung resection
- Diagnosis of COPD, meeting the following criteria:
- FEV\_1/FVC \< 0.71
- Smoking history ≥ 10 pack/years
- Presence of moderate to severe lung disease, meeting 1 of the following:
- FEV\_1 ≤ 60% predicted\*
- FEV\_1\< 80% predicted AND significant shortness of breath defined by a score of 2 or higher in the Medical Research Council Dyspnea Score NOTE: \*Patients with an FEV1 \< 60% predicted (most severe) and scheduled to undergo VATS segmentectomy or wedge resection will also be included.
- PATIENT CHARACTERISTICS:
- Able to physically utilize exercise equipment as part of rehabilitation program
- No poor motivation or likely not to participate fully in PR program
- No recent history (within the past 3 months) of a clinically-significant myocardial infarction, unstable angina, serious cardiac arrhythmia, or other serious medical condition which the attending physician performing the preoperative evaluation deems incompatible with participation in the study
- PRIOR CONCURRENT THERAPY:
- Not specified
Exclusion
Key Trial Info
Start Date :
August 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2012
Estimated Enrollment :
19 Patients enrolled
Trial Details
Trial ID
NCT00363428
Start Date
August 1 2006
End Date
November 1 2012
Last Update
July 19 2017
Active Locations (1)
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1
Mayo Clinic
Rochester, Minnesota, United States, 55905