Status:

COMPLETED

A Study to Demonstrate the Efficacy of GSK Biologicals' Influenza Vaccine in Adults

Lead Sponsor:

GlaxoSmithKline

Conditions:

Influenza

Eligibility:

All Genders

18-64 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to demonstrate the efficacy of GSK Biologicals' influenza vaccine (Fluarix™) administered intramuscularly in adults.

Eligibility Criteria

Inclusion

  • A male or female age between 18 and 64 years at the time of the first vaccination.
  • non-childbearing female

Exclusion

  • Use of non-registered products
  • Pregnancy
  • Hypersensitivity to a previous dose of influenza vaccine
  • Acute disease at the time of enrolment/vaccination.
  • History of allergy or reactions likely to be exacerbated by any component of the vaccine
  • Administration of any other influenza vaccine for the season 2006-2007
  • Chronic disorders of the pulmonary or cardiovascular system, including asthma.
  • Administration of immune-modifying drugs
  • Administration of immunoglobulins and/or any blood products
  • History of requiring regular medical follow-up or hospitalization during the preceding year because of chronic metabolic diseases (including diabetes mellitus), renal dysfunction, hemoglobinopathies, asthma or immunosuppression (including immunosuppression caused by medications or by human immunodeficiency virus)

Key Trial Info

Start Date :

September 1 2006

Trial Type :

INTERVENTIONAL

End Date :

June 1 2007

Estimated Enrollment :

7632 Patients enrolled

Trial Details

Trial ID

NCT00363870

Start Date

September 1 2006

End Date

June 1 2007

Last Update

March 23 2017

Active Locations (15)

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Page 1 of 4 (15 locations)

1

GSK Investigational Site

Hradec Králové, Czechia, 500 03

2

GSK Investigational Site

Espoo, Finland, 02100

3

GSK Investigational Site

Helsinki, Finland, 00100

4

GSK Investigational Site

Helsinki, Finland, 00930