Status:

UNKNOWN

Safety and Efficacy of Ramipril in the Treatment of Essential Hypertension

Lead Sponsor:

Pacific Pharmaceuticals

Conditions:

Essential Hypertension

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The purpose of this study is to assess which drug is more effective of Ramiprin®(ramipril) and Tritace®(ramipril) in the Treatment of Essential Hypertension

Eligibility Criteria

Inclusion

  • mild and moderate essential hypertension (90mmHg≤DBP≤110mmHg)

Exclusion

  • 180mmHg≤SBP
  • If differences greater than 20mmHg for SBP and 10mmHg for DBP between both arms are present on 3 consecutive readings
  • If differences greater than 20mmHg for SBP and 10mmHg for DBP are present on 3 consecutive readings
  • impaired hepatic function
  • imapaired renal function
  • angioedema
  • aortic valvular stenosis or obstrcutive ejection disorder
  • primary hyperaldosteronism
  • renal transplantation, bilateral renal artery stenosis or unilateral stenosis in a single kidney, hemodialysis
  • severe respiratory disease
  • congestive heart failure( New York Association functional class Ⅲ or Ⅳ)
  • malignant hypertension
  • labile angina pectoris or myocardial infarction in the last 3 months before study entry

Key Trial Info

Start Date :

June 1 2006

Trial Type :

INTERVENTIONAL

End Date :

June 1 2007

Estimated Enrollment :

86 Patients enrolled

Trial Details

Trial ID

NCT00366119

Start Date

June 1 2006

End Date

June 1 2007

Last Update

March 9 2007

Active Locations (1)

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1

Seoul National University Hospital

Seoul, 28 Yeongeon-dong, Jongno-gu, South Korea, 110-744