Status:
COMPLETED
Treatment of Cerebral Toxoplasmosis in HIV/AIDS
Lead Sponsor:
Department of Medical Services Ministry of Public Health of Thailand
Collaborating Sponsors:
Chiang Mai University
Conditions:
Toxoplasmic Encephalitis
AIDS
Eligibility:
All Genders
16+ years
Phase:
PHASE4
Brief Summary
Neurological manifestations of Cerebral toxoplasmosis or Toxoplasmic encephalitis (TE) in most advance stage HIV infected patients composed of fever, headache, alteration of consciousness with focal n...
Detailed Description
Background: Toxoplasmic encephalitis (TE), caused by Toxoplasma gondii, is common in AIDS patients. TE can result in tissue destruction via massive inflammation and brain abscess formation. METHODS: R...
Eligibility Criteria
Inclusion
- AIDS
- Age \> 16 years
- Clinical Diagnosis of Cerebral toxoplasmosis, Toxoplasmic encephalitis
- Positive serum titer for Toxoplasma gondii or Positive CSF titer for Toxoplasma gondii after treatment within 2 weeks
- CT scan suspected toxoplasmosis, ring enhancing lesion
- CD4\<200
Exclusion
- Sulfa drugs allergy
- positive lymphoma cell cytology in CSF
- no informed consent by patients or first degreee relatives
- CD4 \>200
Key Trial Info
Start Date :
May 1 2003
Trial Type :
INTERVENTIONAL
End Date :
August 1 2004
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00367081
Start Date
May 1 2003
End Date
August 1 2004
Last Update
July 31 2007
Active Locations (1)
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1
Chiang Mai University hospital (2003-2004)
Chiang Mai, Thailand, 50200