Status:

SUSPENDED

Specific Blockage of Angiotensine 2 and Podocyturia in Glomerular Nephropathies With Hypertension and Proteinuria

Lead Sponsor:

University Hospital, Strasbourg, France

Conditions:

Proteinuria

Hypertension

Eligibility:

All Genders

18-75 years

Phase:

PHASE4

Brief Summary

Chronic glomerular diseases are one of the main causes leading to end stage renal disease (ESRD). Hypertension and proteinuria are two modifiable factors promoting the progression of ESRD. Podocyte ar...

Eligibility Criteria

Inclusion

  • Hypertension (TAs \> 130, TAd \> 80mmHg or under antihypertensive treatment)
  • Glomerular nephropathy, proteinuria \> 1 g/day, serum creatinin \< 200 µmol/L ;
  • Informed consent given ;
  • No contraindication for ARB and hydrochlorothiazide ;
  • Efficient contraception for women

Exclusion

    Key Trial Info

    Start Date :

    August 1 2006

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    Estimated Enrollment :

    20 Patients enrolled

    Trial Details

    Trial ID

    NCT00369538

    Start Date

    August 1 2006

    Last Update

    February 18 2009

    Active Locations (1)

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    Service de Néphrologie, Hôpital Civil, Hôpitaux Universitaires

    Strasbourg, France, 67091