Status:
TERMINATED
Functional Brain Imaging of Medication Treatment Response in Mild Alzheimer's Disease Patients
Lead Sponsor:
Duke University
Collaborating Sponsors:
Ortho-McNeil Neurologics, Inc.
Conditions:
Alzheimer's Disease
Eligibility:
All Genders
40-90 years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine whether standard medications approved for Alzheimer's disease treatment differ in their action on brain functioning and whether any observed brain activity di...
Detailed Description
This study seeks to differentiate task-related and resting brain activity patterns captured via functional magnetic resonance imaging (fMRI) and associated with two common Alzheimer's disease (AD) med...
Eligibility Criteria
Inclusion
- Must meet diagnosis of mild Alzheimer's disease
- Must have a family member or caregiver who is willing to attend all study visits and provide information on your participation in the study
- If female, must be post-menopausal
- Must be able to swallow tablets
Exclusion
- Metal implants or medical devises unsafe for MRI use
- Pre-menopausal female
- HIstory of recent head injury
- Significant major, life-threatening illness or injury (e.g., stroke, AIDS, etc.)
- Vascular dementia or any dementia other than Alzheimer's Disease
- History of significant alcoholism or drug abuse
- History of seizure disorder, developmental delay or major psychiatric illness
Key Trial Info
Start Date :
October 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2007
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT00369603
Start Date
October 1 2006
End Date
November 1 2007
Last Update
April 11 2013
Active Locations (1)
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1
Joseph & Kathleen Bryan Alzheimer's Disease Research Unit
Durham, North Carolina, United States, 27705