Status:

COMPLETED

Diagnostic Usefulness of Fluorine-18-α-Methyltyrosine PET in Combination With 18F-FDG in Sarcoidosis Patient

Lead Sponsor:

Gunma University

Conditions:

Sarcoidosis

Eligibility:

All Genders

Brief Summary

L-\[3-18F\]-α-methyltyrosine (FMT) is amino-acid tracer for positron emission tomography (PET), and is used for tumor detection because malignant tumor cells accumulate 18F-FMT based on the increased ...

Eligibility Criteria

Inclusion

  • Eligible patients were required to have histologically proven noncaseating epithelioid cell granuloma and at least one disease that the possibility of coexistent malignancy could not be excluded as follows; 1) extrapulmonary lesions mimicking malignant diseases including systemic lymphadenopathy, hepatosplenic involvement, or other lesions, 2) multiple nodular lesions mimicking pulmonary metastasis, 3) the occurrence of BHL in cancer patient.

Exclusion

  • The patients that PET imaging using 18F-FDG and 18F-FMT was performed before establishment of the final diagnosis of sarcoidosis, patients undergoing treatment for sarcoidosis before the PET study, and patient having diabetes mellitus.

Key Trial Info

Start Date :

September 1 1998

Trial Type :

OBSERVATIONAL

End Date :

August 1 2005

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00369980

Start Date

September 1 1998

End Date

August 1 2005

Last Update

November 7 2006

Active Locations (1)

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1

Gunma University Graduate School of Medicine

Gunma, Japan, 371-8511