Status:

TERMINATED

HEAL-HF: A Cardiac Resynchronization Therapy (CRT) Outcomes Study

Lead Sponsor:

Stereotaxis

Collaborating Sponsors:

Medtronic

Conditions:

Heart Failure, Congestive

Eligibility:

All Genders

18-80 years

Phase:

PHASE4

Brief Summary

The literature shows that approximately 40% of individuals who receive a cardiac resynchronization therapy (CRT) device for symptomatic congestive heart failure (CHF) do not have a clinical benefit fr...

Detailed Description

Baseline information will be obtained including QoL, 6-minute walk, and echo measurements. The patient will be randomized to receive a conventionally-placed LV lead or randomized to receive a magnetic...

Eligibility Criteria

Inclusion

  • Ischemic cardiomyopathy
  • Ejection Fraction (EF) \<= 35%
  • QRS duration \>= 120 msec
  • Standard heart failure (HF) oral medications for at least 1 month
  • Evidence of mechanical dyssynchrony
  • NYHA Class III or IV

Exclusion

  • Persistent or chronic atrial fibrillation (AF)
  • Hemodynamically unstable or uncontrolled arrhythmias
  • Unstable angina
  • Aortic valve (AV) insufficiency or stenosis
  • Mitral valve (MV) regurgitation \> 2+
  • Active infection
  • Contraindications for heparin
  • Dependence on atrial pacing

Key Trial Info

Start Date :

February 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2007

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT00370526

Start Date

February 1 2007

End Date

December 1 2007

Last Update

January 11 2008

Active Locations (5)

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Page 1 of 2 (5 locations)

1

Northeast Georgia Heart Center, PC

Gainesville, Georgia, United States, 30501

2

Medical University of South Carolina

Charleston, South Carolina, United States, 29425

3

Medical College of Virginia - Virginia Commonwealth University

Richmond, Virginia, United States, 23129

4

University of Ottawa Heart Institute

Ottawa, Ontario, Canada, K1Y 4W7