Status:

COMPLETED

Effect on Glycemic Control of Inhaled Insulin Alone or Added to Dual Oral Therapy After Failure of Dual Oral Therapy.

Lead Sponsor:

Pfizer

Collaborating Sponsors:

Sanofi

Nektar Therapeutics

Conditions:

Diabetes Mellitus, Type 2

Eligibility:

All Genders

35-80 years

Phase:

PHASE3

Brief Summary

To assess the impact on glucose control by inhaled insulin alone or added to two oral anti-diabetic agents in patients with type 2 diabetes who are not well controlled on 2 oral anti-diabetic agents.

Eligibility Criteria

Inclusion

  • Type 2 Diabetes Mellitus as defined by American Diabetes Association (ADA) at least 1 year earlier.
  • Patients were required to have been treated with a stable oral agent regimen involving 2 antidiabetc medications: 1 insulin secretagogue (a sulfonylurea or replabinide) and 1 insulin sensitizer (a thiazolidinedione or metformin).

Exclusion

  • Asthma, COPD
  • Smoking during the previous 6 months

Key Trial Info

Start Date :

June 1 1999

Trial Type :

INTERVENTIONAL

End Date :

September 1 2000

Estimated Enrollment :

345 Patients enrolled

Trial Details

Trial ID

NCT00370565

Start Date

June 1 1999

End Date

September 1 2000

Last Update

February 13 2007

Active Locations (52)

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Page 1 of 13 (52 locations)

1

Pfizer Investigational Site

Irvine, California, United States, 92618

2

Pfizer Investigational Site

Long Beach, California, United States, 90806

3

Pfizer Investigational Site

Los Angeles, California, United States, 90059

4

Pfizer Investigational Site

Los Angeles, California, United States, 90073