Status:

COMPLETED

Antibody Secreting Cell and Cyotokine Profiles in Neonates on ECMO

Lead Sponsor:

The University of Texas Health Science Center, Houston

Collaborating Sponsors:

Memorial Hermann Hospital

Conditions:

Persistent Fetal Circulation Syndrome

Diaphragmatic Hernia

Eligibility:

All Genders

1-30 years

Brief Summary

Infants are placed on ECMO for correction of reversible respiratory failure. Often, because a few of the reasons for respiratory failure show us similar things in the baby, it is difficult to determin...

Detailed Description

Specific Aims Primary Objective 1\. Determine the rise, peak, and fall of immunoglobulin isotype-specific ASC's, and immunoactive proteins (cytokines and chemokines) from sequential samples of periph...

Eligibility Criteria

Inclusion

  • 1\) term newborn infants \>24 hours and ≤ 30 days old 2) Placed on ECMO in the NICU at MHCH 3) Parental consent obtained within 48 hours of being placed on ECMO

Exclusion

  • 1\) Infant \> 30 days old 2) Infant NOT on ECMO 3) Withdrawal of parental consent

Key Trial Info

Start Date :

September 1 2006

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

November 1 2007

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT00371241

Start Date

September 1 2006

End Date

November 1 2007

Last Update

November 5 2020

Active Locations (1)

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Memorial Hermann Hospital

Houston, Texas, United States, 77030