Status:
COMPLETED
Ontario Multidetector Computed Tomographic (MDCT) Coronary Angiography Study (OMCAS)
Lead Sponsor:
St. Joseph's Healthcare Hamilton
Conditions:
Coronary Arteriosclerosis
Cardiomyopathies
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
Multidetector Computed Tomographic Coronary Angiography (MDCTCA) has been recently demonstrated to be accurate and may be used as a potential alternative to conventional invasive coronary angiography,...
Eligibility Criteria
Inclusion
- Group 1
- Valvular heart disease (mitral stenosis, mitral regurgitation, aortic stenosis or aortic insufficiency) or
- Congenital heart disease (i.e. VSD, ASD, PDA) or
- Cardiomyopathy OR
- Group 2
- Intermediate probability of coronary artery disease (probability of 10-90%) after clinical evaluation and traditional non-invasive testing
Exclusion
- Age \< 18 years
- Lack of consent
- Renal Insufficiency (GFR \< 60 mL/min)
- Allergy to contrast agent
- Refractory angina requiring urgent/emergent coronary angiography (as per treating physician)
- Pregnancy or breast feeding
- Uncontrolled heart rate
- Previous CABG or PCI/Stent
- Chronic atrial fibrillation
- History of acute myocardial infarction, as defined by a creatine kinase (CK) level greater than 2 times normal with a troponin level above 4.
- Unable to perform 20 second breath-hold
Key Trial Info
Start Date :
September 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2009
Estimated Enrollment :
168 Patients enrolled
Trial Details
Trial ID
NCT00371891
Start Date
September 1 2006
End Date
June 1 2009
Last Update
November 25 2010
Active Locations (4)
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1
University of Ottawa Heart Institute
Ottawa, Ontario, Canada, K1Y 4W7
2
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada, M4N 3M5
3
St. Michael's Hospital
Toronto, Ontario, Canada, M5B 1W8
4
University Health Network
Toronto, Ontario, Canada, M5G 2C4