Status:

COMPLETED

Ceftriaxone Versus Chloramphenicol for Treatment of Severe Pneumonia in Children

Lead Sponsor:

Makerere University

Conditions:

Pneumonia

Eligibility:

All Genders

6-59 years

Phase:

PHASE3

Brief Summary

Acute lower respiratory tract infections are a leading cause of morbidity and mortality in sub Saharan Africa. The World Health Organisation (WHO) still recommends intravenous chloramphenicol for the ...

Detailed Description

A recent report from the World health Organization showed pneumonia was the leading cause of death in children less than 5 years. WHO recommends intravenous Chloramphenicol 25mg/kg six hourly as the f...

Eligibility Criteria

Inclusion

  • Children aged 6 months to 59months with cough, difficult breathing and lower chest indrawing
  • Consent from parent/carer

Exclusion

  • Children with severe Asthmatic attack
  • Allergy to any of the study drugs
  • Diagnosis of Pneumocystis JiroveciPneumonia on therapeutic treatment

Key Trial Info

Start Date :

September 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2007

Estimated Enrollment :

348 Patients enrolled

Trial Details

Trial ID

NCT00372541

Start Date

September 1 2006

End Date

March 1 2007

Last Update

July 26 2010

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Department of Paediatrics and Child Health, Mulago Hospital

Kampala, East Africa, Uganda, 256

2

Department of Paediatrics and Child Health, Makerere University

Kampala, Kampala, Uganda, P O 7072

3

Department of paediatrics and child Health,Makerere university

Kampala, Kampala, Uganda, P O 7072

4

Department of Paediatrics and Child, Makerere University

Kampala, Kampala, Uganda, P O 7072