Status:
COMPLETED
Increasing Folate Status of a General Population(FOLSUPP STUDY)
Lead Sponsor:
Quadram Institute Bioscience
Collaborating Sponsors:
Food Standards Agency, United Kingdom
University of Sheffield
Conditions:
Healthy
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The aim of this study is to determine the best source of folate to raise the folate status of a general population over a 16 week intervention period.
Detailed Description
This study is designed to assess whether increasing the consumption of natural food folates from a mixed diet is as effective as supplemental folic acid or supplemental natural folate in raising folat...
Eligibility Criteria
Inclusion
- Men and women aged 18-65 years
- Smokers and non-smokers
Exclusion
- Pregnant or has been pregnant within the last 12 months
- Breastfeeding
- Has donated or intends to donate blood within 16 weeks of the first or last study samples
- Fails standard clinical screening of blood and urine for human studies at the Institute of Food Reseach
- BMI above 18 or below 40
- Receiving vascular disease or anti-hypertensive drugs
- Those with diabetes
- Regularly consuming dietary supplements containing B-vitamins and/or folic acid.
- \[As the capsules are prepared from gelatin, true vegetarians may not wish to participate\]
Key Trial Info
Start Date :
May 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2012
Estimated Enrollment :
180 Patients enrolled
Trial Details
Trial ID
NCT00372645
Start Date
May 1 2005
End Date
January 1 2012
Last Update
March 24 2015
Active Locations (2)
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1
Institute of Food Research
Norwich, Norfolk, United Kingdom, NR4 7UA
2
University of Sheffield
Sheffield, Yorkshire, United Kingdom, S10 2FN