Status:
COMPLETED
A Double-Blind Placebo Controlled Trial of Riluzole in Bipolar Depression
Lead Sponsor:
Johns Hopkins University
Collaborating Sponsors:
Stanley Medical Research Institute
Conditions:
Bipolar Disorder
Eligibility:
All Genders
18-75 years
Phase:
PHASE2
Brief Summary
The Johns Hopkins Department of Psychiatry is conducting a research study to examine the effectiveness of riluzole in treating the depressed phase of bipolar disorder. This outpatient treatment study ...
Detailed Description
The study will last 8 to 12 weeks and requires weekly visits. Participants will come to Johns Hopkins for a screening visit during which they will talk with a psychiatrist, answer questions about thei...
Eligibility Criteria
Inclusion
- Ages 18-75
- Diagnosed with Bipolar I or II disorder and currently depressed
- Tried at least one antidepressant during the current episode of depression
- Currently taking either lithium, depakote, or tegretol
- Currently in outpatient treatment with a psychiatrist
Exclusion
- Current psychotic symptoms
- Women who are pregnant or nursing
- Any serious, uncontrolled medical illness
- History of liver problems
- Current or past blood diseases
- Current drug or alcohol abuse
- Currently receiving Electroconvulsive Shock Therapy (ECT)
- Judged to be at serious suicidal risk
Key Trial Info
Start Date :
May 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2010
Estimated Enrollment :
94 Patients enrolled
Trial Details
Trial ID
NCT00376220
Start Date
May 1 2004
End Date
May 1 2010
Last Update
April 11 2017
Active Locations (1)
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1
Johns Hopkins
Baltimore, Maryland, United States, 21205