Status:
COMPLETED
Brain Connectivity Between Visual Input and Movement
Lead Sponsor:
National Institute of Neurological Disorders and Stroke (NINDS)
Conditions:
Occipital Cortex
Prefrontal Cortex
Eligibility:
All Genders
18+ years
Brief Summary
This study will explore how the areas in the brain are connected to link what people see to what they do; that is, how they use what they see to help guide their movements. The study uses functional m...
Detailed Description
OBJECTIVE: The purpose is to analyze task-related connectivity changes in brain regions, using a block design blood oxygenation level-dependent functional magnetic resonance imaging (BOLD-fMRI), as a...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Subjects age 18 and older
- Subjects must be right-hand dominant (Edinburgh Handedness Quotient greater than 60)
- Subjects willing to abstain from caffeine or alcohol for 48 hours prior to the fMRI scanning
- EXCLUSION CRITERIA:
- Subjects with any abnormal findings on neurological exam
- Subjects who are pregnant (as determined by a positive urine pregnancy test)
- Subjects with any finding on the MRI safety questionnaire which prevents them from safely undergoing an MRI scan
- Subjects with metallic dental fillings which are likely to cause MRI artifacts
- Subjects with any history of brain tumor, stroke, head trauma or a vascular malformation as obtained by history or from imaging studies
- Subjects with any history of a severe medical condition, such as cardiovascular disease, which would prevent them from lying flat for up to 120 minutes
- Subjects without the capacity to give informed consent
- Subjects with claustrophobia or other restrictions which prevent them from undergoing a scan in a confined space for up to 60 minutes
Exclusion
Key Trial Info
Start Date :
September 12 2006
Trial Type :
OBSERVATIONAL
End Date :
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT00376545
Start Date
September 12 2006
Last Update
July 2 2017
Active Locations (1)
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1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892