Status:

COMPLETED

Safety and Accuracy of Alveoscopy in Interstitial Lung Diseases

Lead Sponsor:

University Hospital, Rouen

Conditions:

Respiratory Tract Diseases

Eligibility:

All Genders

18+ years

Brief Summary

Fibered confocal fluorescence microscopy (FCFM), also referred to as Cell-Vizio® (MaunaKea Technologies, France) is a new technique that produces microscopic imaging in a living tissue, through a 1 mm...

Detailed Description

The study will include 40 healthy smoker or non-smoker volunteers, 20 patients with normal Chest CT scan and normal respiratory function tests, and 90 patients with focal or diffuse peripheral lung di...

Eligibility Criteria

Inclusion

  • Healthy volunteers: normal chest X-rays and normal lung function tests
  • Patients without parenchymal lung diseases: normal chest computed tomography (CT) scan, normal lung function tests, indication for a bronchoscopy
  • Patients with parenchymal lung disease: indication for a bronchoscopy
  • Written informed consent for the alveoscopy

Exclusion

  • Bleeding disorders
  • Pulmonary hypertension
  • Contraindication for a bronchoscopy
  • known hypersensitivity to the fluorescent contrast agent (if required)

Key Trial Info

Start Date :

May 1 2006

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2013

Estimated Enrollment :

270 Patients enrolled

Trial Details

Trial ID

NCT00377338

Start Date

May 1 2006

End Date

June 1 2013

Last Update

July 30 2013

Active Locations (1)

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Rouen University Hospital

Rouen, Haute Normandie, France, 76000