Status:
WITHDRAWN
The Effects of Probiotics in Atopic Dermatitis
Lead Sponsor:
University of California, Los Angeles
Collaborating Sponsors:
Thrasher Research Fund
Conditions:
Atopic Dermatitis
Eligibility:
All Genders
6-3 years
Phase:
NA
Brief Summary
The purpose of this study is to study the clinical effects of taking probiotics in patients who have moderate to severe atopic dermatitis. There has been several studies showing improvement in the sev...
Detailed Description
The central hypothesis of this study is that a subset of commercially available probiotic formulations will ameliorate moderate to severe atopic dermatitis in children by inducing the development of T...
Eligibility Criteria
Inclusion
- Age between 6 months to 3 years
- Physician diagnosis of moderate to severe atopic dermatitis as defined by the Hanifin and Rajka criteria
- Ability to take enterally commercially available probiotics by powder form added to food or drink
- Ability to undergo venipuncture or dermal puncture (if less than 1 year old)
Exclusion
- Prior exposure to probiotics
- Current antibiotic administration
- Known history of chronic medical condition such as congenital heart disease, liver or kidney disease, or immune deficiency
- Absence of T regulatory cell induction by probiotic bacteria on initial laboratory assessment
- Any other condition in which the Investigators involved in the study determine potential subject is unsuitable for the study
Key Trial Info
Start Date :
July 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2008
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00378300
Start Date
July 1 2007
End Date
June 1 2008
Last Update
March 16 2016
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
UCLA Medical Center
Los Angeles, California, United States, 90095