Status:
TERMINATED
Effect of Paracetamol, Pregabalin and Dexamethasone on Pain and Opioid Requirements in Patients Having a Tonsillectomy
Lead Sponsor:
Glostrup University Hospital, Copenhagen
Conditions:
Pain, Postoperative
Eligibility:
All Genders
18-50 years
Phase:
PHASE4
Brief Summary
Patients scheduled for a tonsillectomy need postoperative pain treatment. Some of the most widely used postoperative analgetics (NSAIDs) sometimes cause rebleeding in the postoperative period, and ano...
Detailed Description
We will investigate the effect of paracetamol versus paracetamol combined with pregabalin versus paracetamol combined with pregabalin and dexamethasone on pain and morphine requirements in the first 2...
Eligibility Criteria
Inclusion
- Patients scheduled for benign tonsillectomy
- Between the ages of 18 and 50 years old
- ASA 1-2 and a surgical technique without the need for local anaesthetics or electrical scissors
Exclusion
- Malignancy
- Patients who are unable to cooperate
- Does not speak Danish
- Has allergy for drugs used in the trial
- Has abused drugs and/or medicine
- Epilepsy
- Diabetes treated with medicine
- Treatment with systemic steroids 4 weeks prior to the operation
- Daily use of antacids
- Daily use of analgesics
- Use of antidepressives
- Known kidney disease
- Pregnancy
Key Trial Info
Start Date :
January 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2009
Estimated Enrollment :
147 Patients enrolled
Trial Details
Trial ID
NCT00378547
Start Date
January 1 2006
End Date
December 1 2009
Last Update
January 1 2010
Active Locations (1)
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1
Department of Day Case Surgery at Glostrup University Hospital
Glostrup Municipality, Denmark, 2600