Status:
COMPLETED
Repository for Inherited Eye Diseases
Lead Sponsor:
National Eye Institute (NEI)
Conditions:
Retinitis Pigmentosa
Inherited Ophthalmic Diseases
Eligibility:
All Genders
1-100 years
Brief Summary
The National Ophthalmic Disease Genotyping and Phenotyping Network (eyeGENE(R)) is a genomic medicine initiative created by the National Eye Institute (NEI), part of the National Institutes of Health ...
Detailed Description
Molecular genetics has the potential to revolutionize the diagnosis and treatment of inherited eye diseases. Progress in research on inherited eye disease would be augmented by the availability of pat...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- To participate in this protocol:
- 1a. The participant must present with characteristics that meet minimal clinical criteria established by eyeGENE, as determined by the referring clinician.
- OR
- 1b. The participant must be a relative of an affected participant if analysis would help with the interpretation of an affected participant's test results or to obtain some useful information as decided by the eyeGENE Research Study Group.
- 2\. The participant must be willing and able to provide a suitable blood sample.
- EXCLUSION CRITERIA:
- Severe systemic disease that compromise the ability of the referring clinician to obtain an adequate eye examination.
- Any disease or condition that makes it unsafe for a subject to provide a blood sample of at least 5 ml for children and at least 15ml for adults.
- Inability to cooperate with phlebotomy and clinical examination.
- Those with impaired decision-making capability who do not have a legally-authorized representative.
- If clinical criteria information, consent forms, or a blood sample can not be provided by the doctor or participant after one year of submitting a blood sample to eyeGENE .
Exclusion
Key Trial Info
Start Date :
September 20 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 19 2015
Estimated Enrollment :
6618 Patients enrolled
Trial Details
Trial ID
NCT00378742
Start Date
September 20 2006
End Date
November 19 2015
Last Update
December 8 2025
Active Locations (1)
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1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892