Status:

COMPLETED

An Open-Label Study of YM087 (Conivaptan) in Patients With Euvolemic or Hypervolemic Hyponatremia

Lead Sponsor:

Cumberland Pharmaceuticals

Conditions:

Hyponatremia

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

This study will investigate the application of a vasopressin antagonist in the treatment of hyponatremia most likely caused by inappropriate AVP secretion. The population studied will include patients...

Eligibility Criteria

Inclusion

  • Serum sodium levels less than or equal 130mEq/L
  • Euvolemic or Hypervolemic hyponatremia

Exclusion

  • Clinical evidence of volume depletion or dehydration
  • Untreated severe hypothyroidism, hyperthyroidism, or adrenal insufficiency
  • Uncontrolled brady-or tachyarrhythmias requiring pacemaker placement or treatment

Key Trial Info

Start Date :

February 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2005

Estimated Enrollment :

251 Patients enrolled

Trial Details

Trial ID

NCT00379847

Start Date

February 1 2004

End Date

June 1 2005

Last Update

May 2 2014

Active Locations (28)

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Page 1 of 7 (28 locations)

1

Tuscon, Arizona, United States, 85723

2

Denver, Colorado, United States, 80262

3

Washington D.C., District of Columbia, United States, 20007

4

Augusta, Georgia, United States, 30901