Status:
COMPLETED
Understanding the Genetic Basis of Atherosclerosis and Peripheral Arterial Disease
Lead Sponsor:
Stanford University
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Peripheral Vascular Diseases
Eligibility:
All Genders
40+ years
Brief Summary
Atherosclerosis, a condition in which fatty deposits build up along the inner walls of arteries, can occur throughout the body. The purpose of this study is to examine the possible genetic differences...
Detailed Description
Plaque build-up caused by atherosclerosis increases the risk of blood clots, heart attack, and stroke. Blockages of plaque can occur in different areas of the body. PAD, a circulatory disorder in whic...
Eligibility Criteria
Inclusion
- Hemodynamically significant PAD, as documented by an ankle-brachial index less than 0.9; control group participants will not have PAD
- Received a referral for an elective coronary angiogram
- Suspected CAD
Exclusion
- History of radiation treatment
- History of organ transplant
- History of viral diseases (i.e. HIV, hepatitis)
Key Trial Info
Start Date :
April 1 2004
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
1789 Patients enrolled
Trial Details
Trial ID
NCT00380185
Start Date
April 1 2004
Last Update
May 28 2015
Active Locations (2)
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1
Stanford University
Stanford, California, United States, 94305
2
Mt. Sinai Medical Center
New York, New York, United States, 10029