Status:

TERMINATED

Open-Label Treatment With MPC-7869 for Patients With Alzheimer's Who Previously Participated in an MPC-7869 Protocol

Lead Sponsor:

Myrexis Inc.

Conditions:

Alzheimer's Disease

Eligibility:

All Genders

55+ years

Phase:

PHASE3

Brief Summary

Open-label treatment with MPC-7869 for participants in a previous randomized study.

Eligibility Criteria

Inclusion

  • Participation in a previous MPC-7869 randomized protocol
  • Have had a diagnosis of probable Alzheimer's disease.
  • Men or women ages 55 years or greater and living in the community at the time of enrollment (i.e., not living in a rest home or nursing care facility).
  • Signed the subject Informed Consent Form and is willing and able to participate for the duration of the study.
  • Female subjects must be surgically sterile or postmenopausal for \> 1 year.
  • Subjects must have a reliable caregiver who can read, understand and speak English or Spanish.

Exclusion

  • History or evidence of, active malignancy, except for basal cell carcinoma or squamous cell carcinoma of the skin, within the 24 months prior to entry. Men with prostate cancer may be enrolled at the discretion of the sponsor.
  • Chronic or acute renal, hepatic or metabolic disorder.
  • Use of any investigational therapy within 30 days, or 5 half-lives, whichever is longer, and/or use of AD immunotherapy prior to screening.

Key Trial Info

Start Date :

September 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2008

Estimated Enrollment :

1000 Patients enrolled

Trial Details

Trial ID

NCT00380276

Start Date

September 1 2006

End Date

December 1 2008

Last Update

August 5 2008

Active Locations (90)

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Page 1 of 23 (90 locations)

1

Alabaster, Alabama, United States

2

Huntsville, Alabama, United States

3

Phoenix, Arizona, United States

4

Sun City, Arizona, United States

Open-Label Treatment With MPC-7869 for Patients With Alzheimer's Who Previously Participated in an MPC-7869 Protocol | DecenTrialz