Status:

COMPLETED

A Study of Semen Characteristics After 9 Months of Daily Tadalafil 20 mg

Lead Sponsor:

Eli Lilly and Company

Collaborating Sponsors:

ICOS Corporation

Conditions:

Erectile Dysfunction

Eligibility:

MALE

45+ years

Phase:

PHASE4

Brief Summary

This is a multicenter, randomized, double-blind, placebo-controlled, fixed dose, parallel design study to evaluate effects on semen characteristics after 40 weeks of daily dosing with 20 mg tadalafil.

Eligibility Criteria

Inclusion

  • Healthy male subjects or men with mild erectile dysfunction
  • At least 45 years of age
  • With specified semen characteristics.

Exclusion

  • Certain chronic medical conditions including cardiac disease, congestive heart failure, kidney or liver disease, cancer and HIV
  • A history of certain endocrine or hormonal abnormalities
  • A history of significant testicular/genital abnormalities
  • Any significant reproductive abnormality identified at the start of the study.

Key Trial Info

Start Date :

November 1 2003

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2005

Estimated Enrollment :

282 Patients enrolled

Trial Details

Trial ID

NCT00382135

Start Date

November 1 2003

End Date

December 1 2005

Last Update

October 25 2007

Active Locations (1)

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For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Bothell, Washington, United States