Status:

COMPLETED

Study Evaluating the Safety and Efficacy of Bazedoxifene in Postmenopausal Asian Women

Lead Sponsor:

Wyeth is now a wholly owned subsidiary of Pfizer

Conditions:

Postmenopause

Osteoporosis

Eligibility:

FEMALE

45+ years

Phase:

PHASE3

Brief Summary

The purpose of this study is to evaluate the effect of 20 mg of bazedoxifene in comparison to placebo on bone mineral density after 6 months of therapy in a population of postmenopausal Asian women.

Eligibility Criteria

Inclusion

  • Generally healthy Asian women 45 years of age or older who are at least 1 year postmenopausal
  • Subjects must qualify for one of the following categories (a or b):
  • Greater than 1 year but less than 5 years postmenopausal with at least one of the ospeoporosis risk factors
  • Equal or greater than 5 years postmenopausal with BMD T-score at lumbar spine or femoral neck between -1 and -2.5 (values of -1 and -2.5 are acceptable) with at least one osteoporosis risk factor

Exclusion

  • One (1) or more osteoporotic vertebral fractures (T4 - L4)
  • BMD T-score at the lumbar spine or femoral neck less than -2.5
  • Past history or active nontraumatic venous thromboembolic events, including deep vein thrombosis, pulmonary embolism, and retinal vein thrombosis

Key Trial Info

Start Date :

May 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2007

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT00384072

Start Date

May 1 2006

End Date

September 1 2007

Last Update

December 28 2007

Active Locations (20)

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Page 1 of 5 (20 locations)

1

Beijing, China, 100700

2

Beijing, China, 100730

3

Nanjing, China, 210008

4

Shanghai, China, 100730