Status:
COMPLETED
Nicotine as an Adjuvant Analgesic for Third Molar Surgery
Lead Sponsor:
Columbia University
Conditions:
Dental Crowding
Eligibility:
All Genders
18-60 years
Phase:
PHASE4
Brief Summary
Third molar surgery is complicated by pain and swelling for several days after surgery. Non-steroidal antiinflammatory drugs have been useful in combination with opioids for treatment. Nicotine has an...
Detailed Description
This is a randomized double blind cross-over study. In each of two sittings, the third molars on one side of the mouth are removed. In one sitting the subject will receive a nicotine nasal spray (3mg)...
Eligibility Criteria
Inclusion
- over 18
- 4 molars to be removed
Exclusion
- pregnant
- lactating
- chronic pain
- narcotic use
- asthma
- ex-smokers
Key Trial Info
Start Date :
July 1 2004
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2009
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00385216
Start Date
July 1 2004
End Date
June 1 2009
Last Update
September 19 2024
Active Locations (1)
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1
Columbia University
New York, New York, United States, 10032